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产品目录

重组小鼠Frizzled-2图片
产品货号:
JN1466
中文名称:
重组小鼠Frizzled-2
英文名称:
Recombinant Mouse frizzled (Drosophila) homolog 2
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln29-Leu168在C端带有Fc标签。

Frizzled-2质量控制:>95%(还原性SDS-PAGE)

Frizzled-2制剂:冻干品

Frizzled-2保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

Frizzled-2复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于Frizzled-2
Wnt signaling plays a critical role in embryonic development, and genetic aberrations. Frizzled2 (Fzd2) is a receptor for wingless-type MMTV integration site family members (Wnts), the aberrant overexpression of which has been noted to contribute to cancer metastasis. Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines and in high-grade tumors and that their expression correlates with markers of epithelial-mesenchymal transition (EMT). It is also shown that Frizzled-2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.
相关搜索:重组小鼠Frizzled-2Recombinant Mouse frizzled (Drosophila) homolog 2
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